ABSTRACT
To determine the accuracy of Fine Needle Aspiration [FNA] cytology in the diagnosis of bone lesions, fifty bone lesions after clinical and radiographic correlation were evaluated by FNA. The results were compared with the histopathology of the open biopsis. Accuracy rates of 75% and 88% were achieved by FNA of non-malignant and malignant bone lesions respectively. Chondrosarcoma and non-malignant lesions such as unicameral bone cyst gave the greatest diagnostic difficulties. Osteosarcoma, Ewing's sarcoma and metastasis could be easily identified when interpreted with clinical and radiographic findings. FNA plays an important role in early diagnosis of most of the malignant bone lesions. Cytologic evaluation together with clinical and radiographic findings has a high accrucy rate for diagnosis of bone lesions